Methoxetamine is one of the new synthetic drugs (“designer drugs,” “research chemicals,” “legal highs”) that are sold online. It is often sold either as ketamine or as one of its derivatives. However, the effects of MXE are different from those of ketamine: they take longer to appear, they are more potent and longer-lasting (see below). Chemically, methoxetamine is close to narcotic drugs such as ketamine and phencyclidine (PCP).