Mixing drugs is taking risks

Mixing drugs with antagonistic desired effects that cancel each other out, whereas the negative effects add up at best, or multiply at worst. Thus, you hardly feel the effects and you can end up taking a lot of drugs without realizing it is leading you to overdose. It is the case for mixes between “upper” drugs (stimulant drugs: ecstasy, speed…) and “downer” drugs (relaxing drugs: alcohol, heroin, ketamine…). It is also the case for cocaine + ecstasy mix and alcohol + ecstasy mix, because alcohol and cocaine conceal the effects of ecstasy. You can end up taking another ecstasy thinking the first one was low-dosed. What’s more, drinking alcohol increases the risk of dehydration and hyperthermia due to ecstasy use.

On the contrary, mixing two products with respiratory depressant or cardiac slowing effects (for instance: ketamine + alcohol ⇒ frequently observed accidents): important risk of fainting or respiratory depression because the risks add up. Beware of the GHB + alcohol mix: high risk of coma

Using ecstasy mixed with cannabis or nitrous oxide (laughing gas) can strengthen the “up” phase or bring down the effects of the “down” ecstasy phase. It can often lead to an extremely powerful “up” phase associated with fainting or “bad trip.”

Mixing speed or cocaine with ketamine (often in the same snort) to be high and remain dynamic. Ketamine increases loss of movement control and conceals the pain, and speed facilitates mobility, increasing the risk of accidents.

However, the comprehensive list is way too long !